Cyclopentolate (hydrochloride)

Cyclopentolate (DL-Cyclopentolate) hydrochloride is an Atropine-like muscarinic receptors antagonist with a pKB value of 7.8 (on the circular ciliary muscle) . Cyclopentolate hydrochloride is an anti-muscarinic agent commonly used in the ophthalmologic practice[1][2].

Product Specifications

CAS Number

[5870-29-1]

Product Name Alternative

DL-Cyclopentolate (hydrochloride)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

MAChR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/cyclopentolate-hydrochloride.html

Purity

99.54

Solubility

DMSO : 250 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

O=C(OCCN(C)C)C(C1(O)CCCC1)C2=CC=CC=C2.[H]Cl

Molecular Formula

C17H26ClNO3

Molecular Weight

327.85

Precautions

H302, H315, H319, H335

References & Citations

[1]Öner V, Bulut A, Öter K. The effect of topical anti-muscarinic agents on subfoveal choroidal thickness in healthy adults. Eye (Lond) . 2016;30 (7) :925‐928.|[2]Ishikawa H, DeSantis L, Patil PN. Selectivity of muscarinic agonists including (+/-) -aceclidine and antimuscarinics on the human intraocular muscles. J Ocul Pharmacol Ther. 1998;14 (4) :363‐373.|[3]Öner V, Bulut A, Öter K. The effect of topical anti-muscarinic agents on subfoveal choroidal thickness in healthy adults. Eye (Lond) . 2016;30 (7) :925‐928.