RPC10 Rabbit Polyclonal Antibody

This gene encodes a small essential subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The carboxy-terminal domain of this subunit shares a high degree of sequence similarity to the carboxy-terminal domain of an RNA polymerase II elongation factor. This similarity in sequence is supported by functional studies showing that this subunit is required for proper pausing and termination during transcription. Pseudogenes of this gene are found on chromosomes 13 and 17.[provided by RefSeq, Jul 2010], function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs., similarity:Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family., similarity:Contains 1 TFIIS-type zinc finger., subunit:Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.