CDK5 (Phospho-Ser159) Rabbit Polyclonal Antibody

Catalytic activity:ATP + a protein = ADP + a phosphoprotein., function:Probably involved in the control of the cell cycle. Interacts with D1 and D3-type G1 cyclins. Can phosphorylate histone H1, tau, MAP2 and NF-H and NF-M. Also interacts with p35 which activates the kinase., similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily., similarity:Contains 1 protein kinase domain., subcellular location:In axonal growth cone with extension to the peripheral lamellipodia., subunit:Heterodimer of a catalytic subunit and a regulatory subunit (p35) . Found in a trimolecular complex with CABLES1 and ABL1. Interacts with CABLES1 (By similarity) . Interacts with AATK.

Cyclin-dependent kinase 5 (EC 2.7.11.22) (Cell division protein kinase 5) (Serine/threonine-protein kinase PSSALRE) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit)