ACO2 Rabbit Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15 (PRSS15), also known as Lon protease, after oxidative modification. [provided by RefSeq, Jul 2008], catalytic activity:Citrate = isocitrate., cofactor:Binds 1 4Fe-4S cluster per subunit. Binding of a 3Fe-4S cluster leads to an inactive enzyme., online information:Aconitase entry, pathway:Carbohydrate metabolism; tricarboxylic acid cycle., similarity:Belongs to the aconitase/IPM isomerase family., subunit:Monomer.
Product Name Alternative
Aconitate hydratase, mitochondrial (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase)
Gene Name
ACO2
Gene ID
50
Swiss Prot
Q99798
Host
Rabbit
Reactivity
Human, Mouse, Rat, Canine
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, ELISA
Field of Research
Citrate cycle (TCA cycle) ; Glyoxylate and dicarboxylate metabolism
Purification
Affinity purification
Dilution
WB 1:500-1:2000, ELISA 1:5000-1:10000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
90kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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