GRB7 Rabbit Polyclonal Antibody
Product Specifications
Background
The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK) . Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2011], alternative products:At least 2 isoforms are produced, function:Interacts with the cytoplasmic domain of the epidermal growth factor receptor which is then inhibited. The interaction is mediated by the SH2 domain. Also binds to ERBB2., PTM:Phosphorylated on tyrosine residues., similarity:Belongs to the GRB7/10/14 family., similarity:Contains 1 PH domain., similarity:Contains 1 Ras-associating domain., similarity:Contains 1 SH2 domain., subunit:Interacts with RND1.
Product Name Alternative
Growth factor receptor-bound protein 7 (B47; Epidermal growth factor receptor GRB-7; GRB7 adapter protein)
Gene Name
GRB7
Gene ID
2886
Swiss Prot
Q14451
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC, ICC/IF, ELISA
Purification
Affinity purification
Dilution
IHC 1:50-1:200, ICC/IF 1:50-1:200, ELISA 1:10000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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