CdcA3 Rabbit Polyclonal Antibody
Product Specifications
Background
Domain:The KEN box is required for the association with the APC/C-Cdh1 complex., function:F-box-like protein which is required for entry into mitosis. Acts by participating to E3 ligase complexes that mediate the ubiquitination and degradation of WEE1 kinase at G2/M phase., pathway:Protein modification; protein ubiquitination., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., PTM:Ubiquitinated and degraded by the APC/C-Cdh1 complex., subunit:Interacts with SKP1A. Part of a SCF (SKP1-cullin-F-box) protein ligase complex., domain:The KEN box is required for the association with the APC/C-Cdh1 complex., function:F-box-like protein which is required for entry into mitosis. Acts by participating to E3 ligase complexes that mediate the ubiquitination and degradation of WEE1 kinase at G2/M phase., pathway:Protein modification; protein ubiquitination., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., PTM:Ubiquitinated and degraded by the APC/C-Cdh1 complex., subunit:Interacts with SKP1A. Part of a SCF (SKP1-cullin-F-box) protein ligase complex.
Product Name Alternative
CDCA3; C8; GRCC8; TOME1; Cell division cycle-associated protein 3; Gene-rich cluster protein C8; Trigger of mitotic entry protein 1; TOME-1
Gene Name
CDCA3
Gene ID
83461
Swiss Prot
Q99618
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:200-1:1000, ELISA 1:5000-1:10000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
28kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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