PDE4C Rabbit Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011], catalytic activity:Adenosine 3',5'-cyclic phosphate + H (2) O = adenosine 5'-phosphate., enzyme regulation:Inhibited by rolipram., pathway:Purine metabolism; cAMP degradation; AMP from cAMP: step 1/1., similarity:Belongs to the cyclic nucleotide phosphodiesterase family., tissue specificity:Expressed in various tissues but not in cells of the immune system.
Product Name Alternative
PDE4C; DPDE1; cAMP-specific 3'; 5'-cyclic phosphodiesterase 4C; DPDE1; PDE21
Gene Name
PDE4C
Gene ID
5143
Swiss Prot
Q08493
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ELISA
Field of Research
Purine metabolism
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:2000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
80kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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