HMG-1 (Acetyl Lys12) Rabbit Polyclonal Antibody
Product Specifications
Background
This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2015], function:Binds preferentially single-stranded DNA and unwinds double stranded DNA., similarity:Belongs to the HMGB family., similarity:Contains 2 HMG box DNA-binding domains.
Product Name Alternative
HMGB1; HMG1; High mobility group protein B1; High mobility group protein 1; HMG-1
Gene Name
HMGB1
Gene ID
3146
Swiss Prot
P09429
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Field of Research
Base excision repair
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:5000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Acetylated
Molecular Weight
About 30kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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