Cerberus Rabbit Polyclonal Antibody

This gene encodes a cytokine member of the cysteine knot superfamily, characterized by nine conserved cysteines and a cysteine knot region. The cerberus-related cytokines, together with Dan and DRM/Gremlin, represent a group of bone morphogenetic protein (BMP) antagonists that can bind directly to BMPs and inhibit their activity. [provided by RefSeq, Jul 2008], function:Cytokine that may play a role in anterior neural induction and somite formation during embryogenesis in part through a BMP-inhibitory mechanism. Can regulate Nodal signaling during gastrulation as well as the formation and patterning of the primitive streak., PTM:N-glycosylated., sequence caution:Translated as Ser., similarity:Belongs to the DAN family., similarity:Contains 1 CTCK (C-terminal cystine knot-like) domain., subunit:Forms monomers and predominantly dimers.