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Beclin 1 Rabbit Monoclonal Antibody

Product Specifications

Background

Cell localization:Cytoplasm.beclin 1 (BECN1) Homo sapiens This gene encodes a protein that regμLates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in mμLtiple cellμLar processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing resμLts in mμLtiple transcript variants. [provided by RefSeq, Sep 2015]

Product Name Alternative

Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197)

Gene Name

BECN1 GT197

Gene ID

8678

Swiss Prot

Q14457

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF, ELISA, IP

Purification

Protein A

Dilution

WB 1:2000-1:10000, IHC 1:200-1:1000, ICC/IF 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200

Form

Liquid

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Modification

Unmodified

Molecular Weight

CalcμLated MW:52kD; Observed MW:60kD

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG, Kappa

Available Sizes

Curated Selection

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