DC371739
DC371739 is a potent and orally activity PCSK9 inhibitor. DC371739 decreases the mRNA expression of PCSK9 and ANGPTL3. DC371739 decreases the protein expression of PCSK9 and increases the protein expression of LDLR. DC371739 has the potential for the research of hyperlipidemia[1][2].
Product Specifications
UNSPSC
12352005
Target
ANGPTL; PCSK9
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/dc371739.html
Purity
95.56
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
OCN1C2=C(C3=C1CN4CCC5=CC(OCC6=CC=CC=C6)=C(C=C5C4C3)OC)C=C(OC)C=C2
Molecular Formula
C29H30N2O4
Molecular Weight
470.56
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-163794/DC371739-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-163794/DC371739-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
Phase 1
CAS Number
[2135765-21-6]
Available Sizes
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