KDM4-IN-3
Product Specifications
UNSPSC Description
KDM4-IN-3 is a KDM4 inhibitor that exhibits improved potency in biochemical assays, is cell-permeable, and kills prostate cancer cells at low micromolar concentrations.
Target Antigen
Histone Demethylase
Type
Reference compound
Related Pathways
Epigenetics
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kdm4-in-3.html
Purity
99.36
Solubility
DMSO : 116.67 mg/mL (ultrasonic)
Smiles
OC1=C(C2=CC=CC=C2)C(C)=NN1C3=NC4=CC=CC=C4N3
Molecular Weight
290.32
References & Citations
[1]Carter DM, et al. Enhanced Properties of a Benzimidazole Benzylpyrazole Lysine Demethylase Inhibitor: Mechanism-of-Action, Binding Site Analysis, and Activity in Cellular Models of Prostate Cancer. J Med Chem. 2021 Oct 14;64(19):14266-14282.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-132896/KDM4-IN-3-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-132896/KDM4-IN-3-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1068515-53-6
Available Sizes
Curated Selection
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