NMDAR/TRPM4-IN-2
NMDAR/TRPM4-IN-2 is a potent interfacial inhibitor of NMDAR/TRPM4 interaction.NMDAR/TRPM4-IN-2 protects against MCAO-induced brain damage and NMDA-induced retinal ganglion cell loss in mice.NMDAR/TRPM4-IN-2 has neuroprotective activity against NMDA-induced hippocampal neuronal cell death and mitochondrial dysfunction. NMDAR/TRPM4-IN-2 showed neuroprotective activity against NMDA-induced cell death and mitochondrial dysfunction in hippocampal neurons with an IC50 value of 2.1 μM.
Product Specifications
CAS Number
2243506-33-2
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
330.092
Molecular Formula
C11H19BrCl2N2
Notes
Research use only, not for human use.
Receptor
ERK | TRP/TRPV Channel | iGluR | NMDAR
Available Sizes
Curated Selection
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