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EIPA

EIPA (L593754, MH 12-43) is a TRPP3 channel inhibitor (IC50: 10.5 μM) . It also inhibits Na+/H+-exchanger (NHE) and macropinocytosis.It is found that EIPA, benzamil, and phenamil rapidly and reversibly block Ca2+-activated TRPP3 channel activation at -50 mV, with IC50s of 143, 10.5, 1.1, and 0.14 μM, respectively.

Product Specifications

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

299.76

Molecular Formula

C11H18ClN7O

Notes

Research use only, not for human use.

Receptor

TRPP3 channel| Na+/H+-exchanger (NHE)

CAS Number

1154-25-2

Available Sizes

Curated Selection

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