Estrone

Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells[1][2].

Product Specifications

CAS Number

[53-16-7]

Product Name Alternative

E1; Oestrone

UNSPSC

12352005

Hazard Statement

H351, H362

Target

Endogenous Metabolite; Estrogen Receptor/ERR

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Endocrinology; Cancer

Assay Protocol

https://www.medchemexpress.com/Estrone.html

Concentration

10mM

Purity

99.96

Solubility

DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : < 0.1 mg/mL (ultrasonic)

Smiles

C[C@]1([C@](CC2)([H])[C@]3([H])CCC4=C(C=CC(O)=C4)[C@@]3([H])CC1)C2=O

Molecular Formula

C18H22O2

Molecular Weight

270.37

Precautions

H351, H362

References & Citations

[1]Caupos E, et al. Photodegradation of estrone enhanced by dissolved organic matter under simulated sunlight. Water Res. 2011;45 (11) :3341-3350.|[2]de Padua Mansur A, et al. Long-term prospective study of the influence of estrone levels on events in postmenopausal women with or at high risk for coronary artery disease. ScientificWorldJournal. 2012;2012:363595.