4-CMTB

4-CMTB is a selective free fatty acid receptor 2 (FFA2/GPR43) agonist and a positive allosteric modulator (pEC50=6.38) [1].

Product Specifications

CAS Number

[300851-67-6]

UNSPSC

12352005

Hazard Statement

H302, H319

Target

Free Fatty Acid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/4-cmtb.html

Purity

99.66

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(NC1=NC=CS1)C(C(C)C)C2=CC=C(Cl)C=C2

Molecular Formula

C14H15ClN2OS

Molecular Weight

294.80

Precautions

H302, H319

References & Citations

[1]Smith NJ, et al. Extracellular loop 2 of the free fatty acid receptor 2 mediates allosterism of a phenylacetamide ago-allosteric modulator. Mol Pharmacol. 2011;80 (1) :163-173.|[2]Milligan G, Stoddart LA, Smith NJ. Agonism and allosterism: the pharmacology of the free fatty acid receptors FFA2 and FFA3. Br J Pharmacol. 2009;158 (1) :146-153.