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Neoseptin 3

Neoseptin 3 is a Toll-like receptor 4/myeloid differentiation factor 2 (mTLR4/MD-2) agonist with an EC50 of 18.5 μM.

Product Specifications

CAS Number

[1622863-21-1]

UNSPSC

12352005

Hazard Statement

H413

Target

Toll-like Receptor (TLR)

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Neoseptin_3.html

Purity

99.21

Solubility

DMSO : ≥ 100 mg/mL

Smiles

CC(C)(C)OC([C@H](CCC1=CC=CC=C1)NC(C2=CC(CCC3=CC=C(O)C=C3)=C(N)C=C2)=O)=O

Molecular Formula

C29H34N2O4

Molecular Weight

474.59

Precautions

H413

References & Citations

[1]Wang Y, et al. TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS. Proc Natl Acad Sci U S A. 2016 Feb 16;113 (7) :E884-93.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

TLR4

Available Sizes

Curated Selection

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