Human CCL11 (Eotaxin-1) Recombinant Protein

The Human CCL11 yeast-derived recombinant protein is not tagged and is naturally endotoxin-free. The purity is greater than 98% as visualized by SDS-PAGE analysis. Human CCL11 applications are for cell culture, ELISA standard, and Western Blot Control. Human CCL11 yeast-derived recombinant protein can be purchased in multiple sizes. Human CCL11 Specifications: (Molecular Weight: 8.4 kDa) (Amino Acid Sequence: GPASVPTTCC FNLANRKIPL QRLESYRRIT SGKCPQKAVI FKTKLAKDIC ADPKKKWVQD SMKYLDQKSP TPKP (74) ) (Gene ID: 6356) . For research use only.

Product Specifications

Background

CCL11 belongs to the CC chemokine family and is commonly known as Eotaxin-1. There are at least 27 distinct members of the C-C subgroup reported for mammals. CC chemokines induce the migration of monocytes and other cell types such as NK cells and dendritic cells. CCL11 selectively recruits eosinophils by inducing their chemotaxis, and therefore, is implicated in allergic responses. Endothelial cells, smooth muscle cells, epithelial cells, alveolar macrophages and eosinophils are known to produce CCL11.