Equine IL-10 Recombinant Protein

The Equine IL-10 yeast-derived recombinant protein is not tagged and is naturally endotoxin-free. The purity is greater than 98% as visualized by SDS-PAGE analysis. Equine IL-10 applications are for cell culture, ELISA standard, and Western Blot Control. The Equine IL-10 yeast-derived recombinant protein can be purchased in multiple sizes. Equine IL-10 Specifications: (Molecular Weight: 18.6 kDa) (Amino Acid Sequence: SRDRGTQSEN SCTHFPTSLP HMLHELRAAF SRVKTFFQMK DQLDNMLLNG SLLEDFKGYL GCQALSEMIQ FYLEEVMPQA ENHGPDIKEH VNSLGEKLKT LRVRLRRCHR FLPCENKSKA VEQVKSAFSK LQEKGVYKAM SEFDIFINYI EAYMTTKMKN (160) ) (Gene ID: 100034187) . For research use only.

Product Specifications

Background

IL-10 has multiple, pleiotropic, effects in immunoregulation and inflammation. It downregulates the expression of Th1 cytokines, MHC class II antigens, and co-stimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. The IL-10 family of cytokines consists of nine members: IL-10, IL-19, IL-20, IL-22, IL-24, IL-26, IL-28A, IL-28B, and IL-29. These cytokines elicit diverse host defense mechanisms. IL-10 family cytokines are essential for maintaining the integrity and homeostasis of tissue epithelial layers. By promoting inamte immune response, members of this family can limit the damage caused by viral and bacterial infections. They can also facilitate the tissue-healing process in injuries caused by infection or inflammation. IL-10 itself is an anti-inflammatory cytokine. IL-10 family cytokines have indispensable functions in many infectious and inflammatory diseases.