Rabbit APRIL Recombinant Protein

The Rabbit APRIL yeast-derived recombinant protein is not tagged and is naturally endotoxin-free. The purity is greater than 98% as visualized by SDS-PAGE analysis. Rabbit APRIL applications are for cell culture, ELISA standard, and Western Blot Control. The Rabbit APRIL yeast-derived recombinant protein can be purchased in multiple sizes. Rabbit APRIL Specifications: (Molecular Weight: 16.5 kDa) (Amino Acid Sequence: ALPTQKQKKK RSLLHLVPIN ITSKEDSDVT EVMWQPALRR GRGLEAQGYV VRVWDTGVYL LYSQVLFHDV TFTMGQVVSR EGQGRQETLF RCVCSMPSDP DRAYNSCYSA GVFHLHQGDI LSVVIPRARA KFSLSPHGTF LGFVKL (146) ) (Gene ID: 100126074) . For research use only.

Product Specifications

Background

Tumor necrosis factor ligand superfamily member 13 also known as a proliferation-inducing ligand (APRIL) is a member of the tumor necrosis factor ligand (TNF) ligand family. Nineteen cytokines have been identified as part of the TNF family on the basis of sequence, functional, and structural similarities. Family members include TNF beta (TNFSF1), TNF alpha, Lymphotoxin beta (TNFSF3), OX40 Ligand (TNFSF4), CD40 Ligand (TNFSF5), Fas Ligand (TNFSF6), CD27 Ligand (TNFSF7), CD30 Ligand (TNFSF8), 4-1BB Ligand (TNFSF9), TRAIL (TNFSF10), TRANCE/RANKL (TNFSF11), TWEAK (TNFSF12), APRIL (TNFSF13), BAFF, LIGHT (TNFSF14), TL1A/VEGI (TNFSF15), and GITR Ligand (TNFSF18) . APRIL/TNFSF13 is expressed by macrophages and dendritic cells. APRIL has been shown to play a role in protecting cells from undergoing apoptosis and promoting B cell development.