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Cynomolgus Monkey TIM-3 Polyclonal Antibody - Biotinylated

The Cynomolgus Monkey TIM-3 polyclonal antibody is labeled and has been qualified for use in ELISA applications. It is the detection antibody in the Kingfisher Biotech Cynomolgus Monkey TIM-3 ELISA. The Cynomolgus Monkey TIM-3 antibody was produced in rabbits and is antigen-affinity purified. This antibody has shown no cross-reactivity with bat, bovine, dolphin, or mouse TIM-3 proteins. For research use only.

Product Specifications

Background

TIM-3 is a transmembrane protein of T lymphocytes (CD4+ and CD8+ T cells), myeloid cells (monocytes, macrophages, DC, mast cells, NK cells) or various cells in different tumor types. The receptor is an immune checkpoint and together with other inhibitory receptors including programmed cell death protein 1 (PD-1) and lymphocyte activation gene 3 protein (LAG3) mediate the CD8+ T-cell exhaustion in terms of proliferation and secretion of cytokines such as TNF-alpha, IFN-gamma and IL-2.

Host

Rabbit

Label

Biotin

Applications

ELISA, ELISpot, Flow Cytometry, Neutralization, Western Blot

Purification

Antigen-affinity

Homology

Macaca fascicularis (crab-eating macaque)

Storage Temperature

2°C to 8°C

Scientific Category

Antibody

Available Sizes

Curated Selection

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