Equine IL-4 Monoclonal Antibody (clone K0003E-1)
IL-4 induces differentiation of naive helper T cells (Th0 cells) to Th2 cells. Upon activation by IL-4, Th2 cells subsequently produce additional IL-4. IL-4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of CD4+ T-cells into Th2 cells. It is a key regulator in humoral and adaptive immunity. IL-4 induces B-cell class switching to IgE, and up-regulates MHC class II production. Overproduction of IL-4 is associated with allergies.
Product Specifications
Background
Host
Mouse
Label
Unconjugated
Applications
ELISA, Flow Cytometry
Homology
Equus asinus (ass), Equus caballus (horse), Equus przewalskii (Przewalski's horse), Equus zebra hartmannae (Hartmann's mountain zebra)
Storage Temperature
2°C to 8°C
Scientific Category
Antibody
Available Sizes
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