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Equine IL-4 Monoclonal Antibody (clone K0003E-1)

IL-4 induces differentiation of naive helper T cells (Th0 cells) to Th2 cells. Upon activation by IL-4, Th2 cells subsequently produce additional IL-4. IL-4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of CD4+ T-cells into Th2 cells. It is a key regulator in humoral and adaptive immunity. IL-4 induces B-cell class switching to IgE, and up-regulates MHC class II production. Overproduction of IL-4 is associated with allergies.

Product Specifications

Background

IL-4 induces differentiation of naive helper T cells (Th0 cells) to Th2 cells. Upon activation by IL-4, Th2 cells subsequently produce additional IL-4. IL-4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of CD4+ T-cells into Th2 cells. It is a key regulator in humoral and adaptive immunity. IL-4 induces B-cell class switching to IgE, and up-regulates MHC class II production. Overproduction of IL-4 is associated with allergies.

Host

Mouse

Label

Unconjugated

Applications

ELISA, Flow Cytometry

Homology

Equus asinus (ass), Equus caballus (horse), Equus przewalskii (Przewalski's horse), Equus zebra hartmannae (Hartmann's mountain zebra)

Storage Temperature

2°C to 8°C

Scientific Category

Antibody

Available Sizes

Curated Selection

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