Isosorbide

Isosorbide (D-Isosorbide), an orally active vasodilating agent that can be used for the research of heart failure and angina (chest pain) . Isosorbide is also an oral hyperosmotic diuretic[1][2].

Product Specifications

CAS Number

[652-67-5]

Product Name Alternative

D-Isosorbide; Dianhydro-D-glucitol

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Metabolic Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/Isosorbide.html

Purity

99.22

Solubility

DMSO : ≥ 100 mg/mL|H2O : ≥ 100 mg/mL

Smiles

O[C@H]1[C@]2([H])[C@]([C@@H](O)CO2)([H])OC1

Molecular Formula

C6H10O4

Molecular Weight

146.14

Precautions

H302, H315, H319, H335

References & Citations

[1]Rose M, et, al. Isosorbide as a renewable platform chemical for versatile applications--quo vadis? ChemSusChem. 2012 Jan 9;5 (1) :167-76.|[2]Nozawa I, et, al. Efficacy of long-term administration of isosorbide for Ménière's disease. ORL J Otorhinolaryngol Relat Spec. May-Jun 1995;57 (3) :135-40.|[3]Newman RA, et, al. Gallium nitrate (NSC-15200) induced toxicity in the rat: a pharmacologic, histopathologic and microanalytical investigation. Cancer. 1979 Nov;44 (5) :1728-40.