HDAC2 Rabbit mAb
This is a HDAC2 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA.
Synonyms
HDAC2; HD2; Histone deacetylase 2; RPD3; YAF1; YY1 associated factor 1
Swiss Prot
Q92769
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human HDAC2
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IHC, ICC/IF, IP, FC
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:1000-1:2000, IHC 1:50-1:100, ICC/IF 1:50-1:100, IP 1:30, FC 1:50
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Curated Selection
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