HCK (Phospho-Tyr522) Antibody

This is a HCK (Phospho-Tyr522) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

The protein encoded by this gene is a protein-tyrosine kinase that is predominantly expressed in hemopoietic cell types. The encoded protein may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Alternate translation initiation site usage, including a non-AUG (CUG) codon, results in the production of two different isoforms, that have different subcellular localization.

Synonyms

P59-HCK/p60-HCK; Hemopoietic cell kinas; Tyrosine-protein kinase HCK

Gene ID

3055

Swiss Prot

P08631

Reactivity

Human

Immunogen

Peptide sequence around phosphorylation site of tyrosine 522 (S-Q-Y (p) -Q-Q) derived from Human HCK.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Phospho-Specific Antibody

Applications

Purification Method

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.