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ATX968

Product Specifications

UNSPSC Description

ATX968 (example 31) is an inhibitor of ATP-dependent RNA helicase A (DHX9), with the EC50 of 0.054 μM in circBRIP1. ATX968 has antitumor activity[1].

Target Antigen

DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

cancer

Assay Protocol

https://www.medchemexpress.com/dhx9-in-2.html

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

ClC1=CC(NC(C2=CC(C3=NC=CC=C3C)=CS2)=O)=CC(NS(C)(=O)=O)=C1

Molecular Weight

421.92

References & Citations

[1]DANIELS Matthew H., et al. Preparation of imidazopyridines, thienopyrimidines, pyrrolopyrimidines and related heterocycles as inhibitors of RNA helicase DHX9 useful in treatment of cancers. World Intellectual Property Organization, WO2023154519 A1 2023-08-17

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-156784/ATX968-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-156784/ATX968-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

2973395-71-8

Available Sizes

Curated Selection

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