Myostatin-Propeptide
Mature Myostatin is obtained by proteolytic processing of a biologically-inactive precursor protein, which contains an N-terminal propeptide of 243 amino acid residues. Myostatin Propeptide exhibits high binding affinity for myostatin and has been shown to be a potent inhibitor of Myostatin. Over-expression of myostatin propeptide in mice resulted in large increases (up to 200%) in skeletal muscle mass, similar to those observed in Myostatin knockout mice. Recombinant Human Myostatin Propeptide is a 27.8 kDa protein consisting of 244 amino acid residues.
Product Specifications
Synonyms
MSTN; GDF8; MSLHP
NCBI Gene ID
2660
UniProt
O14793
Accession Number
NP_005250.1
Accession Number mRNA
NM_005259.2
Chromosomal Location
2q32.2
Reactivity
Human
Cross Reactivity
Mouse
Sequence
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Length
244
Form
Lyophilized
Molecular Weight
27.8 kDa
Host or Source
E. coli
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