CD23 Antibody [Tü1]
Product Specifications
Background
CD23 is a 45 kDa type II integral membrane glycoprotein that is the low affinity receptor for IgE. It also binds to CD21 and the alpha chains of CD11b and CD11c. It is expressed by B cells and monocytes and, weakly, on T cells, follicular dendritic cells, eosinophils, NK cells, Langerhans cells, and platelets. It is upregulated in response to B cell activation, CD40 ligation, or in response to IL-4 or IL-13. CD23 is responsible for regulation of IgE synthesis and may play a role in antigen presentation by B cells and follicular dendritic cells by interacting with CD40.
NCBI Gene ID
2208
Swiss Prot
P06734
Accession Number
P06734
Host
Mouse
Reactivity
Human
Immunogen
Purified human tonsil lymphocytes
Clonality
Monoclonal
Clone
[Tü1]
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Stem Cell, Cancer, Cell Cycle
Concentration
0.1 mg/mL
Buffer
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store vial at 2-8˚ C
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=99-499
Fragment
IgG3
Specificity
CD23
Applications Notes
CD23 Antibody [Tü1] for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, and blocking assays.
Symbol
FCER2
NCBI Official Name
Fc fragment of IgE, low affinity II, receptor for (CD23)
NCBI Organism
Homo sapiens
Other Product Names
FCepsilonRII, B6, Leu-20, BLAST-2, low affinity IgE receptor
Tested Applications
Flow
Physical Properties
Liquid
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