CUEDC2 Antibody

Product Specifications

Background

Down-regulates ESR1 protein levels through the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol. Also involved in 17 beta-estradiol-induced ESR1 degradation. Controls PGR protein levels through a similar mechanism.

NCBI Gene ID

79004

Swiss Prot

Q9H467

Accession Number

NP_076945.2

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

CUEDC2 antibody was raised against a peptide sequence around aa.262~266 (D-V-R-N-P) derived from Human CUEDC2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cancer

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

32 kDa

Specificity

This antibody detects endogenous level of total CUEDC2 protein.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

CUEDC2

NCBI Official Name

CUE domain containing 2

NCBI Organism

Homo sapiens

Background Reference 01

Zhang P. -J., Zhao J., Li H. -Y., Man J. -H., He K., Zhou T., Pan X., Li A. -L., Gong W. -L., Jin B. -F., Xia Q., Yu M., Shen B. -F., Zhang X. -M. EMBO J. 26:1831-1842 (2007)