LGR5 Antibody

Product Specifications

Background

Orphan receptor. Stem cell marker of the intestinal epithelium and the hair follicule. Target gene of Wnt signaling.

NCBI Gene ID

8549

Swiss Prot

O75473

Accession Number

NP_003658.1

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

LGR5 (GPR49) antibody was raised against a peptide sequence around aa.490~494 (K-I-S-N-Q) derived from Human LGR5 (GPR49) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Stem Cell

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

95 kDa

Specificity

This antibody detects endogenous level of total LGR5 (GPR49) protein.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

LGR5

NCBI Official Name

Leucine-rich repeat containing G protein-coupled receptor 5

NCBI Organism

Homo sapiens

Background Reference 01

Yamamoto Y., Sakamoto M., Fujii G., Tsuiji H., Kenetaka K., Asaka M., Hirohashi S. Hepatology 37:528-533 (2003) McClanahan T., Koseoglu S., Smith K., Grein J., Gustafson E., Black S., Kirschmeier P., Samatar A. A. Cancer Biol. Ther. 5:419-426 (2006) Becker L., Huang Q., Mashimo H. Scientific World Journal 8:1168-1176 (2008)