MAP2 Antibody

Product Specifications

Background

The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.

NCBI Gene ID

4133

Swiss Prot

P11137

Accession Number

NP_002365.3

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

MAP2 antibody was raised against a peptide sequence around aa.1819~1823 (T-A-A-L-A) derived from Human MAP2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Stem Cell

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

55 - 75 (2c/2d), 280 (2a/2b) kDa

Specificity

This antibody detects endogenous level of total MAP2 protein.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

MAP2

NCBI Official Name

Microtubule-associated protein 2

NCBI Organism

Homo sapiens

Background Reference 01

DeGiorgis J. A., Jaffe H., Moreira J. E., Carlotti C. G. Jr., Leite J. P., Pant H. C., Dosemeci A. J. Proteome Res. 4:306-315 (2005) Olsen J. V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M. Cell 127:635-648 (2006) Matsuoka S., Ballif B. A., Smogorzewska A., McDonald E. R. III, Hurov K. E., Luo J., Bakalarski C. E., Zhao Z., Solimini N., Lerenthal Y., Shiloh Y., Gygi S. P., Elledge S. J. Science 316:1160-1166 (2007)