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MELK Antibody

Product Specifications

Background

Phosphorylates ZNF622 and may contribute to its redirection to the nucleus. May be involved in the inhibition of spliceosome assembly during mitosis.

NCBI Gene ID

9833

Swiss Prot

Q14680

Accession Number

NP_055606.1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

MELK antibody was raised against a peptide sequence around aa.626~630 (I-R-R-Q-R) derived from Human MELK.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Stem Cell

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

74 kDa

Specificity

This antibody detects endogenous level of total MELK protein.

Applications Notes

Western Blot: 1:500

Symbol

MELK

NCBI Official Name

Maternal embryonic leucine zipper kinase

NCBI Organism

Homo sapiens

Background Reference 01

Seong H. -A., Gil M., Kim K. -T., Kim S. -J., Ha H. Biochem. J. 361:597-604 (2002) Vulsteke V., Beullens M., Boudrez A., Keppens S., Van Eynde A., Rider M. H., Stalmans W., Bollen M. J. Biol. Chem. 279:8642-8647 (2004)

Other Product Names

HPK38, hPK38, KIAA0175, hMELK

Tested Applications

WB

Protein ID

7661974

Physical Properties

Liquid

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