CDCP1 (CD318) Antibody

Product Specifications

Background

May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis.

NCBI Gene ID

64866

Swiss Prot

Q9H5V8

Accession Number

NP_073753.3

Host

Rabbit

Reactivity

Human

Immunogen

CDCP1 (CD318) antibody was raised against a peptide sequence around aa.828~832 (T-Q-E-P-M) derived from Human CDCP1 (CD318) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Stem Cell

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

140 kDa

Specificity

This antibody detects endogenous level of total CDCP1 (CD318) protein.

Applications Notes

Western Blot: 1:500

Symbol

CDCP1

NCBI Official Name

CUB domain containing protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Scherl-Mostageer M., Sommergruber W., Abseher R., Hauptmann R., Ambros P., Schweifer N. Oncogene 20:4402-4408 (2001) Bhatt A. S., Erdjument-Bromage H., Tempst P., Craik C. S., Moasser M. M. Oncogene 24:5333-5343 (2005) Xia Y., Gil S. G., Carter W. G. J. Cell Biol. 132:727-740 (1996)