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CD44 Antibody

Product Specifications

Background

Receptor for hyaluronic acid (HA) . Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs) . Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.

NCBI Gene ID

960

Swiss Prot

P16070

Accession Number

NP_000601.3

Host

Rabbit

Reactivity

Human, Rat

Immunogen

CD44 antibody was raised against a peptide sequence around aa.734~738 (Q-N-V-D-M) derived from Human CD44.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Stem Cell

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

80 kDa

Specificity

This antibody detects endogenous level of total CD44 protein.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

CD44

NCBI Official Name

CD44 molecule (Indian blood group)

NCBI Organism

Homo sapiens

Background Reference 01

Teriete P., et. al (2004) Mol. Cell 13:483-496 Bartolazzi A. (2003) Melanoma Res. 13:325-337Liu T. et. al (2005) J. Proteome Res. 4:2070-2080

Other Product Names

IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1, CDW44, CSPG8, HCELL, HUTCH-I, ECMR-III

Tested Applications

WB

Protein ID

48255935

Physical Properties

Liquid

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