SOX2 Antibody

Product Specifications

Background

Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency

NCBI Gene ID

6657

Swiss Prot

P48431

Accession Number

NP_003097.1

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

SOX2 antibody was raised against a peptide sequence around aa.76~80 (G-A-E-W-K) derived from SOX2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Stem Cell

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

35 kDa

Specificity

This antibody detects endogenous level of total SOX2 protein.

Applications Notes

Western Blot: 1:1000

Symbol

SOX2

NCBI Official Name

SRY (sex determining region Y) -box 2

NCBI Organism

This antibody was raised against a peptide sequence around aa.76~80 (G-A-E-W-K) derived from SOX2

Background Reference 01

Yuan H, et al. Genes Dev. 1995 Nov 1;9 (21) : 2635-45Muta M, et al. Genes Cells 2002 Aug;7 (8) : 791-805 Tomioka M, et al. Nucleic Acids Res. 2002 Jul 15; 30 (14) : 3202-3213.