Macroglobulin Antibody

Product Specifications

Background

Chicken polyclonal IgY Antibodies against α -2 macroglobulin. Human serum protein. A broad range irreversible proteinase inhibitor that forms a "trap" around most proteases. a2M is so large a molecular that is tends to remain intravascular. Localized on the surface of peripheral blood lymphocytes, M.W: 725,000.

NCBI Gene ID

Swiss Prot

P01023

Accession Number

Mahu

Host

Chicken

Reactivity

Human, Mouse, Rat

Immunogen

Full-length (plasma protein)

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

Antigen affinity-purified

Concentration

1 mg/mL

Buffer

Phosphate-Buffered Saline. No preservatives added.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Macroglobulin antibody can be stored at 4˚ C for short term (weeks) . Long term storage should be at -20˚ C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

163.3 kDa (calculated)

Applications Notes

Macroglobulin antibody can be used for the detection of Macroglobulin by Western blot, ELISA, IP, may also work for IHC and ICC.

Symbol

A2M

NCBI Official Name

Alpha-2-macroglobulin

NCBI Organism

Homo sapiens

Background Reference 01

Dolmer, K., Jenner, L. B., Jacobsen, L., Andersen, G. R., Koch, T. J., Thirup, S., Sottrup-Jensen, L. and Nyborg, J. Crystallisation and preliminary X-ray analysis of the receptor-binding domain of human and bovine alpha 2-macroglobulin FEBS Lett. 372 (1), 93-95 (1995) .