M6PR Antibody

Product Specifications

Background

Chicken polyclonal IgY Antibodies against cation-dependent mannose-6-phosphate receptor. This protein is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein that localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane.

NCBI Gene ID

4074

Swiss Prot

P20645

Accession Number

NP_002346.1

Host

Chicken

Reactivity

Human, Mouse, Rat

Immunogen

60-114

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

Antigen affinity-purified

Concentration

1 mg/mL

Buffer

Phosphate-Buffered Saline. No preservatives added.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

M6PR antibody can be stored at 4˚ C for short term (weeks) . Long term storage should be at -20˚ C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

31 kDa (calculated)

Applications Notes

M6PR antibody can be used for the detection of M6PR by ICC, may also work for IHC.

Symbol

M6PR

NCBI Official Name

Mannose-6-phosphate receptor (cation dependent)

NCBI Organism

Homo sapiens

Background Reference 01

Klumperman, J. et al. Differences in the endosomal distributions of the two mannose 6-phosphate receptors J. Cell Biol. 121 (5), 997-1010 (1993)

Other Product Names

MPR46, MPRD, Cation-dependent mannose-6-phosphate receptor, 46 kDa mannose 6-phosphate receptor, CD Man-6-P receptor, SMPR, MPR46, CD-MPR, MPR 46, MPR-46