IL-1a Antibody [1F3B3]
Product Specifications
Background
Interleukin-1alpha is a member of the interleukin 1 cytokine family. It is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. IL-1 alpha and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.
NCBI Gene ID
3552
Swiss Prot
P01583
Accession Number
P01583
Host
Mouse
Reactivity
Human
Immunogen
Ni-NTA purified recombinant human IL-1α expressed in E. Coli strain BL21 (DE3) .
Clonality
Monoclonal
Clone
1F3B3
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Innate Immunity, Neuroscience
Concentration
Batch dependent
Buffer
Ascitic fluid containing 0.03% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
IL-1a monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=32-178
Fragment
IgG2a
Symbol
IL1A
NCBI Official Name
Interleukin 1, alpha
NCBI Organism
Homo sapiens
Background Reference 01
Du, Y.; et al. 2000. Neurology 55: 480-484.
Background Reference 02
Grimaldi, L. et al. Ann. Neurol. 47: 361-365, 2000.
Other Product Names
IL1F1, Hematopoietin-1, IL-1 alpha, IL1, IL-1A, IL1F1, IL1-ALPHA
Tested Applications
ELISA, WB
Protein ID
124297
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