CD8 Antibody [RAVB3]
Product Specifications
Background
CD8 T cell surface antigen is heterodimer of an alpha and a beta chain linked by two disulfide bonds .It belongs type I membrane protein. Selectively expressing of CD8 on a subset of T cells leads to CD8 T cell development. Through identifying cytotoxic/suppressor T-cells that interact with MHC class I bearing targets, CD8 is thought to play a role in the process of T-cell mediated killing. Veillette et al (1988) found the CD8 is associated with the internal membrane tyrosine-protein kinase p56lck.
NCBI Gene ID
925
Swiss Prot
P01732
Accession Number
P01732
Host
Mouse
Reactivity
Human
Immunogen
Ni-NTA purified recombinant human CD8 expressed in E. Coli strain BL21 (DE3) .
Clonality
Monoclonal
Clone
RAVB3
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
Antibody is purified by protein A affinity chromatography.
Concentration
Batch dependent
Buffer
Purified antibody in PBS containing 0.03% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
CD8 monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=32-134
Fragment
IgG1
Symbol
CD8A
NCBI Official Name
CD8a molecule
NCBI Organism
Homo sapiens
Background Reference 01
Veillette, A. et al. 1988. Cell 55:301.
Other Product Names
MALCD8, MAL, p32, Leu2
Tested Applications
ELISA, WB
Protein ID
116035
Curated Selection
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