ETS2 Antibody
Product Specifications
Background
ETS transcriptions factors, such as ETS2, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes.
NCBI Gene ID
2114
Swiss Prot
P15036
Accession Number
P15036
Host
Rabbit
Reactivity
Human
Immunogen
This ETS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 146-173 amino acids from the Central region of human ETS2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
53 kDa
Fragment
Rabbit Ig
Symbol
ETS2
NCBI Official Name
Protein C-ets-2
NCBI Organism
Homo sapiens
Background Reference 01
Zabuawala, T., et al. Cancer Res. 70 (4) :1323-1333 (2010)
Background Reference 02
Yerges, L.M., et al. J. Bone Miner. Res. 24 (12) :2039-2049 (2009)
Background Reference 03
Shalaby, A.A., et al. Mod. Pathol. 22 (8) :996-1005 (2009)
Background Reference 04
Sutter, W., et al.Craniomaxillofac Surg 37 (5) :263-271 (2009)
Other Product Names
Protein C-ets-2, ETS2
Tested Applications
WB, IHC-P, Flow
Protein ID
119645
Physical Properties
Liquid
Curated Selection
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