PIGN Antibody

Product Specifications

Background

PIGN is involved in glycosylphosphatidylinositol (GPI) -anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is expressed in the endoplasmic reticulum and transfers phosphoethanolamine (EtNP) to the first mannose of the GPI anchor.

NCBI Gene ID

23556

Swiss Prot

O95427

Accession Number

O95427

Host

Rabbit

Reactivity

Human

Immunogen

This PIGN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 206-235 amino acids from the N-terminal region of human PIGN.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

106 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PIGN

NCBI Official Name

GPI ethanolamine phosphate transferase 1

NCBI Organism

Homo sapiens

Background Reference 01

McDonough, C.W., et al. Hum. Genet. (2009) In press :

Background Reference 02

Oh, J.H., et al. Mamm. Genome 16 (12) :942-954 (2005)

Background Reference 03

Kinoshita, T., et al. Curr Opin Chem Biol 4 (6) :632-638 (2000)

Background Reference 04

Hong, Y., et al. J. Biol. Chem. 274 (49) :35099-35106 (1999)

Other Product Names

GPI ethanolamine phosphate transferase 1, 2---, MCD4 homolog, Phosphatidylinositol-glycan biosynthesis class N protein, PIG-N, PIGN, MCD4

Tested Applications

Physical Properties

Liquid

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