PRUNE Antibody
Product Specifications
Background
Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. It plays a role in cell proliferation, is able to induce cell motility and acts as a negative regulator of NME1.
NCBI Gene ID
58497
Swiss Prot
Q86TP1
Accession Number
Q86TP1
Host
Rabbit
Reactivity
Human
Immunogen
This PRUNE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 360-389 amino acids from the C-terminal region of human PRUNE.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
50 kDa
Fragment
Rabbit Ig
Symbol
PRUNE
NCBI Official Name
Protein prune homolog
NCBI Organism
Homo sapiens
Background Reference 01
Vieira, A.R., et al. Genet. Med. 10 (9) :668-674 (2008)
Background Reference 02
Middelhaufe, S., et al. Biochem. J. 407 (2) :199-205 (2007)
Background Reference 03
Kobayashi, T., et al. Mol. Cell. Biol. 26 (3) :898-911 (2006)
Background Reference 04
Zollo, M., et al. Clin. Cancer Res. 11 (1) :199-205 (2005)
Other Product Names
Protein prune homolog, hPrune, Drosophila-related expressed sequence 17, DRES-17, DRES17, HTcD37, PRUNE
Tested Applications
WB, IHC-P, Flow
Protein ID
229462737
Physical Properties
Liquid
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