TBCE Antibody

Product Specifications

Background

Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.

NCBI Gene ID

6905

Swiss Prot

Q15813

Accession Number

Q15813

Host

Rabbit

Reactivity

Human

Immunogen

This TBCE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 364-392 amino acids from the Central region of human TBCE.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

59 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TBCE

NCBI Official Name

Tubulin-specific chaperone E

NCBI Organism

Homo sapiens

Background Reference 01

Biernacki, M.A., et al. Cancer Res. 70 (3) :906-915 (2010)

Background Reference 02

Padidela, R., et al. J. Clin. Endocrinol. Metab. 94 (8) :2686-2691 (2009)

Background Reference 03

Lindgren, C.M., et al. PLoS Genet. (6), E1000508 (2009)

Background Reference 04

Jin, S., et al. Development 136 (9) :1571-1581 (2009)

Other Product Names

Tubulin-specific chaperone E, Tubulin-folding cofactor E, TBCE

Tested Applications

Protein ID

74762146

Physical Properties

Liquid

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