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KCE1L Antibody

Product Specifications

Background

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a membrane protein which has sequence similarity to the KCNE1 gene product, a member of the potassium channel, voltage-gated, isk-related subfamily. This intronless gene is deleted in AMME contiguous gene syndrome and may be involved in the cardiac and neurologic abnormalities found in the AMME contiguous gene syndrome.

NCBI Gene ID

23630

Swiss Prot

Q9UJ90

Accession Number

Q9UJ90

Host

Rabbit

Reactivity

Human

Immunogen

This KCE1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-96 amino acids from the Central region of human KCE1L.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

15 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

KCNE1L

NCBI Official Name

Potassium voltage-gated channel subfamily E member 1-like protein

NCBI Organism

Homo sapiens

Background Reference 01

Ravn, L.S., et al. Heart Rhythm 5 (3) :427-435 (2008)

Background Reference 02

Lundquist, A.L., et al. Genomics 87 (1) :119-128 (2006)

Background Reference 03

Ravn, L.S., et al. Am. J. Cardiol. 96 (3) :405-407 (2005)

Background Reference 04

Yang, Y., et al. Am. J. Hum. Genet. 75 (5) :899-905 (2004)

Other Product Names

Potassium voltage-gated channel subfamily E member 1-like protein, AMME syndrome candidate gene 2 protein, KCNE1L, AMMECR2

Tested Applications

WB

Physical Properties

Liquid

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