ING5 Antibody
Product Specifications
Background
ING5 is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in TP53-dependent regulatory pathway. [provided by RefSeq].
NCBI Gene ID
84289
Swiss Prot
Q8WYH8
Accession Number
Q8WYH8
Host
Rabbit
Reactivity
Human
Immunogen
This ING5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-119 amino acids from the Central region of human ING5.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
28 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ING5
NCBI Official Name
Inhibitor of growth protein 5
NCBI Organism
Homo sapiens
Background Reference 01
Ullah, M., et al. Mol. Cell. Biol. 28 (22) :6828-6843 (2008)
Background Reference 02
Champagne, K.S., et al. Proteins 72 (4) :1371-1376 (2008)
Background Reference 03
Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)
Other Product Names
Inhibitor of growth protein 5, p28ING5, ING5
Tested Applications
WB
Protein ID
57012960
Physical Properties
Liquid
Curated Selection
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