GRB7 Antibody

Product Specifications

Background

GRB7 belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK) .

NCBI Gene ID

2886

Swiss Prot

Q14451

Accession Number

Q14451

Host

Rabbit

Reactivity

Human

Immunogen

This GRB7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 289-318 amino acids from the Central region of human GRB7.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

60 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

GRB7

NCBI Official Name

Growth factor receptor-bound protein 7

NCBI Organism

Homo sapiens

Background Reference 01

Depetris, R.S., et al. Nat. Struct. Mol. Biol. 16 (8) :833-839 (2009)

Background Reference 02

Chu, P.Y., et al. J. Biol. Chem. 284 (30) :20215-20226 (2009)

Background Reference 03

Mavaddat, N., et al. Cancer Epidemiol. Biomarkers Prev. 18 (1) :255-259 (2009)

Background Reference 04

Bai, T., et al. Carcinogenesis 29 (3) :473-479 (2008)

Other Product Names

Growth factor receptor-bound protein 7, B47, Epidermal growth factor receptor GRB-7, GRB7 adapter protein, GRB7

Tested Applications

Protein ID

116242503

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

RC223913 10 µg

DEFB123 (NM_153324) Human Tagged ORF Clone

Ask

View Details

A53110-50UL 50 μL

DLX4 Antibody

Ask

View Details

MF-0109181-01 10 g

Oxalic acid (calcium monohydrate)

Ask

View Details

MF-0109181-02 5 g

Oxalic acid (calcium monohydrate)

Ask

View Details

MF-0109181-03 50 g

Oxalic acid (calcium monohydrate)

Ask

View Details

NB100-55322AF350 0.1 mL

Rabbit Polyclonal ZRANB2 Antibody [Alexa Fluor 350]

Ask

View Details