DBC1 Antibody

Product Specifications

Background

DBC1 is located within a chromosomal region that shows loss of heterozygosity in some bladder cancers. It contains a 5' CpG island that may be a frequent target of hypermethylation, and it may undergo hypermethylation-based silencing in some bladder cancers.

NCBI Gene ID

1620

Swiss Prot

O60477

Accession Number

O60477

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This DBC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-111 amino acids from the N-terminal region of human DBC1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

89 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

BRINP1

NCBI Official Name

BMP/retinoic acid-inducible neural-specific protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Koyama, S., et al. Biochem. Biophys. Res. Commun. 392 (3) :357-362 (2010)

Background Reference 02

Gronbaek, K., et al. Mod. Pathol. 21 (5) :632-638 (2008)

Background Reference 03

Louhelainen, J.P., et al. Oncogene 25 (16) :2409-2419 (2006)

Background Reference 04

Izumi, H., et al. Hum. Mol. Genet. 14 (8) :997-1007 (2005)

Other Product Names

BMP/retinoic acid-inducible neural-specific protein 1, Deleted in bladder cancer protein 1, BRINP1, DBC1, DBCCR1, FAM5A

Tested Applications

Physical Properties

Liquid

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