CTSD Antibody
Product Specifications
Background
CTSD encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript.
NCBI Gene ID
1509
Swiss Prot
P07339
Accession Number
P07339
Host
Rabbit
Reactivity
Human
Immunogen
This CTSD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 377-408 amino acids from the C-terminal region of human CTSD.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Neuroscience, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
45 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CTSD
NCBI Official Name
Cathepsin D
NCBI Organism
Homo sapiens
Background Reference 01
Christensen, B., et al. J. Biol. Chem. 285 (11) :7929-7937 (2010)
Background Reference 02
Albayrak, O., et al. J. Gerontol.Biol. Sci. Med. Sci. 65 (3) :219-224 (2010)
Background Reference 03
Heinrich, M., et al. EMBO J. 18 (19) :5252-5263 (1999)
Other Product Names
Cathepsin D, Cathepsin D light chain, Cathepsin D heavy chain, CTSD, CPSD
Tested Applications
WB
Protein ID
115717
Physical Properties
Liquid
Curated Selection
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