COG2 Antibody

Product Specifications

Background

COG2 encodes a subunit of the conserved oligomeric Golgi complex that is required for maintaining normal structure and activity of the Golgi complex. The encoded protein specifically interacts with the USO1 vesicle docking protein and may be necessary for normal Golgi ribbon formation and trafficking of Golgi enzymes.

NCBI Gene ID

22796

Swiss Prot

Q14746

Accession Number

Q14746

Host

Rabbit

Reactivity

Human

Immunogen

This COG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-124 amino acids from the N-terminal region of human COG2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

83 kDa

Fragment

Rabbit Ig

Symbol

COG2

NCBI Official Name

Conserved oligomeric Golgi complex subunit 2

NCBI Organism

Homo sapiens

Background Reference 01

Edwards, T.L., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 150B (5), 721-735 (2009)

Background Reference 02

Luke, M.M., et al. Stroke 40 (2) :363-368 (2009)

Background Reference 03

Shiffman, D., et al. Arterioscler. Thromb. Vasc. Biol. 28 (1) :173-179 (2008)

Background Reference 04

Sohda, M., et al. Traffic 8 (3) :270-284 (2007)

Other Product Names

Conserved oligomeric Golgi complex subunit 2, COG complex subunit 2, Component of oligomeric Golgi complex 2, Low density lipoprotein receptor defect C-complementing protein, COG2, LDLC